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Stable Isotopes - Labeled Compounds

Labelled compounds: The use of labelled compounds free from any contamination (by the active pharmaceutical ingredient API) is essential to the studies value by MS assays. It’ important to have sufficient isotopes (Deuterieum, 13C or 15N) to avoid any analyte contamination and isotope overlapping. The positions of deuterium incorporation by reactions exchange or from the commercially available labelled compounds is specifically choosen to maintain the isotopic level inchanged during the quantitative MS assays. The Metabolic positions and the presence of halogens in compounds are considered with a particular attention, like in examples below.

Used by CRO’s and Pharmaceutical companies

deuterated standards 

Studied by CRO’s and Agrochemical companies

labeled agrochemicals

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